Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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406
Tocris Bioscience™ Rasagiline mesylate
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CAS: 161735-79-1 Molecular Formula: C13H17NO3S
| CAS | 161735-79-1 |
|---|---|
| Molecular Formula | C13H17NO3S |
407
Tocris Bioscience™ MS 154
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Potent and selective cereblon-recruiting Degrader (PROTAC™) of mutant EGFR
408
Tocris Bioscience™ A 804598
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CAS: 1125758-85-1 Molecular Formula: C19H17N5
| CAS | 1125758-85-1 |
|---|---|
| Molecular Formula | C19H17N5 |
409
Tocris Bioscience™ VH 032 amide-PEG4-acid
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VHL ligand with PEG linker and terminal acid for onward chemistry
410
Tocris Bioscience™ Nor NOHA monoacetate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Arginase inhibitor
411
Tocris Bioscience™ Lovastatin
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CAS: 75330-75-5 Molecular Formula: C24H36O5
| CAS | 75330-75-5 |
|---|---|
| Molecular Formula | C24H36O5 |
412
Tocris Bioscience™ Pomalidomide 4'-alkylC8-acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry
413
Tocris Bioscience™ ML 145
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CAS: 1164500-72-4 Molecular Formula: C24H22N2O5S2
| CAS | 1164500-72-4 |
|---|---|
| Molecular Formula | C24H22N2O5S2 |
414
Tocris Bioscience™ ARN 14494
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent serine palmitoyltransferase inhibitor
| Target | Other Transferase Inhibitors |
|---|---|
| CAS | 1037834-43-7 |
| Purity | 0.98 |
| Chemical Name or Material | rel-1-[1-[2-[(3 aR,6 AS)-Hexahydrocyclopenta[c]pyrrol-2(1 H)-yl]-2-oxoethyl]-4-piperidinyl]-2,3-dihydro-N-methyl-2-oxo-1 H-indole-5-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H32N4O3 |
415
Tocris Bioscience™ Paroxetine maleate
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Highly potent and selective 5-HT uptake inhibitor
| Inhibitors | Paroxetine maleate |
|---|---|
| Product Type | Paroxetine maleate |
| Molecular Weight (g/mol) | 445.44 |
| Purity | >99% |
416
Tocris Bioscience™ Ex 26
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Potent and selective S1P1 receptor antagonist
| CAS | 144678-63-7 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Color | White |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C28H28ClFN2O3 |
| Formula Weight | 494.98 |
417
Tocris Bioscience™ GMB 475
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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BCR-ABL1 kinase PROTAC™
418
Tocris Bioscience™ Thalidomide 4'-ether-alkylC6-azide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
419
Tocris Bioscience™ SJ 1008066
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction
420
Tocris Bioscience™ BSJ-4-116-NC
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for BSJ-4-116 (Cat. No. 7528).